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Priyam Bordoloi: The Biological Advantage of Two X Chromosomes
Aug 27, 2026, 06:58

Priyam Bordoloi: The Biological Advantage of Two X Chromosomes

Priyam Bordoloi, Internal Medicine Resident, shared a post on X:

“Women have two X chromosomes.

That brings some real advantages, and a few problems too.

Benefit 1:

  • If one X carries a harmful mutation, the other can sometimes compensate.

That is why haemophilia and Duchenne muscular dystrophy are far more common in men.

Benefits 2 and 3:

  • Women are genetic mosaics. In different cells, a different X remains active, giving the body more cellular diversity.
  • The X also carries many immune genes. Women often develop stronger responses to many infections and vaccines.”

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