Adrien Jossart: Acute Thrombotic Storm Following Single Heparin Bolus
Adrien Jossart, Cardiologue interventionnel at CHU HELORA, shared a post on LinkedIn about a recent article by Justine Massart et al, published in Case Reports in Cardiology, adding:
“New Publication in Case Reports in Cardiology
We look at a severe complication in the cath lab:
a 67 year old patient who developed Type II Heparin Induced Thrombocytopenia (HIT) following a single diagnostic heparin bolus during a routine angiogram.
Within hours, the patient suffered an acute arterial thrombotic storm spanning multiple vascular beds imb ischemia, inferior STEMI, and ischemic stroke.
A few practical reminders from this case:
- Severe arterial thrombosis can hit well before platelets drop below normal thresholds. A 50 percent relative drop is the real red flag.
- Post bolus acute distress is easily misdiagnosed as contrast allergy, delaying the crucial decision to stop heparin.
- When clinical suspicion (4T score) is high, don’t wait on functional assays switch immediately to non heparin anticoagulants.”
Title: Explosive Multiterritorial Arterial Thrombosis Following Brief Heparin Exposure: A Diagnostic Pitfall in the Cath Lab
Authors: Justine Massart, Claudiu Ungureanu, Yves Dascotte, Jacques Auslender, Adrien Jossart 
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