Ohanna Cavalcanti Bezerra: Why Does DVT Lead to PE in Some Patients but Not Others?
Ohanna Cavalcanti Bezerra, Postdoctoral Fellow in (Epi)Genomics at Data Sciences Institute, University of Toronto and Dalla Lana School of Public Health, University of Toronto, VESS Organizing Committee Member at Atlas of Variant Effects Alliance, Member of CANSSI Ontario, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Journal of Thrombosis and Haemostasis, adding:
“Why do some people who develop a deep vein thrombosis (DVT) go on to experience a pulmonary embolism (PE), while others do not?
Our study suggests that genetics plays a role in the development of PE among individuals with a presumed DVT, although the overall genetic effect appears to be modest.”
Title: Genetic associations with pulmonary embolism among those with a deep vein thrombosis: the International Network Against Venous Thrombosis Consortium
Authors: Susana Lozano-Esparza, Gabrielle E. Shakt, Jennifer A. Brody, Angel Martinez-Perez, Matthew P. Conomos, Marine Germain, Katharine R. Clapham, Maris Teder-Laving, Astrid van Hylckama Vlieg, Anni Kauko, Florian Thibord, Ohanna C.L. Bezerra, Girish N. Nadkarni, Gaëlle Munsch, Therese Haugdahl Nøst, Ellen L. Goode, Yuekai Ji, Daniel I. Chasman, Alexander P. Reiner, Constance Turman, Kerri L. Wiggins, Colleen M. Sitlani, Juan Carlos Souto, Pamela L. Lutsey, Tiffany Bellomo, Estonian Biobank, Million Veteran Program, Ruifang Li-Gao, Aleksi Kristian Winstén, Ming-Huei Chen, Ron Do, Lénaick Gourhant, Kristian Hveem, Sebastian M. Armasu, Noémie Saut, Nathan Pankratz, Franco Giulianini, Jeffrey Haessler, Mingyang Song, Robert Olaso, Eric Boerwinkle, Daniel Dochtermann, Jose Manuel Soria, Stephen S. Rich, David Smadja, Satoshi Koyama, Frits R. Rosendaal, Teemu Niiranen, France Gagnon, Ha My T. Vy, Neil Zakai, Catherine Lemarie, Anne Heidi Skogholt, Jean-François Deleuze, James S. Pankow, Paul M. Ridker, Yuxi Liu, Kenneth M. Rice, Saiju Pyarajan, Mary Cushman, Jospeh Emmerich, Bruce M. Psaty, Pradeep Natarajan, Andrew D. Johnson, Marc A. Rodger, Pierre Suchon, Francis Couturaud, Pierre-Emmanuel Morange, Weihong Tang, Charles Kooperberg, Christopher Kabrhel, Maria Sabater-Lleal, David-Alexandre Trégouët, Alisa S. Wolberg, Scott M. Damrauer, Nicholas L. Smith
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