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Digital Twin Study Predicts Higher Thrombotic Recurrence with DOACs vs VKAs in APS Patients
APS Support UK/X
Sep 5, 2025, 06:28

Digital Twin Study Predicts Higher Thrombotic Recurrence with DOACs vs VKAs in APS Patients

APS Support UK has shared a post on X:

“A digital twin model (n=89) assessed thrombotic recurrence in APS treated with DOACs vs VKAs.
DOACs: 24.2% recurrence
VKAs: 19.9%
Risk higher with DOACs in triple-positive and arterial cases.
Comparable in non-triple-positive and venous.”

Title: A Digital Twin Strategy to Predict Thrombotic Recurrence in Antiphospholipid Syndrome Patients Treated with Direct Oral Anticoagulants vs. Vitamin K Antagonists Using Data from Real-World Populations

Authors: Miguel Ángel Casado-Suela, Juan Torres-Macho, Aida Izquierdo-Martínez, Cristina Lucía Ancos-Aracil, Luis Ferreira-Burguillos, Elena Madroñal-Cerezo, Tamar Talaván-Zañón, Adela Castañeda-Mata, Luis Escobar-Curbelo, Ana Martínez de la Casa-Muñoz, Eva Ruiz-Navío, Ana Bustamante-Fermosel, Anabel Franco-Moreno

VKAs

Read the full paper here.

Discover more on Hemostasis Today.

Adela Castañeda-Mata Aida Izquierdo-Martínez Ana Bustamante-Fermosel Ana Martínez de la Casa-Muñoz Anabel Franco-Moreno Antiphospholipid Syndrome Cristina Lucía Ancos-Aracil Direct Oral Anticoagulants DOAC Elena Madroñal-Cerezo Eva Ruiz-Navío Hematology Hemostasis Hemostasis Today Juan Torres-Macho Luis Escobar-Curbelo Luis Ferreira-Burguillos Miguel Ángel Casado-Suela Tamar Talaván-Zañón thrombosis Thrombotic venous thromboembolism Vitamin K antagonists VKA
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