Jamie Nash։ RBC-Derived EVs Show Greater Procoagulant Potential
Jamie Nash, Postdoctoral Research Scientist at Welsh Blood Service, Member of UK Young Academy, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in RPTH, adding:
”Happy to see the abstract I presented at ISTH in Paris this year has now been published in RPTH.
In this pilot study, we reported that RBC-derived EV from end-of-storage red cell concentrates demonstrated greater procoagulant potential than platelet-derived EV.
Time-expired RBC units contained approximately twice the EV load of platelet concentrates and exhibited increased thrombin-generating capacity, suggesting that transfusion of older RBC units may introduce a greater procoagulant burden.”
Title: PB3719 Extracellular Vesicle Concentration and Thrombin Generation: A Comparison of Red Cell and Platelet Concentrate Units
Authors: Jamie Nash, Edward Sayers, Christine Saunders, Chloe George
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