Bruno Pougault/LinkedIn
Oct 5, 2026, 12:51
Bruno Pougault: The Hidden Challenges Behind Anti Xa Testing
Bruno Pougault, Global Marketing Hemostasis Product Manager at HORIBA ABX SAS, shared a post on LinkedIn:
“New episode out now on Hemostasis Pulse! Is your Anti-Xa assay giving you the true physiological picture of your patient?
In this new episode, we explore the critical importance of Anti-Xa reagent selection and pre-analytical rigor for heparin monitoring (UFH amp; LMWH), fully grounded in guidelines from learned societies (ISTH, BSH, SFH, SFTH, and ASH).
What you will learn in this episode:
- Why traditional aPTT falls short due to acute-phase reactants and lupus anticoagulant interferences.
- The Dextran Sulfate Trap: How certain Anti-Xa reagents artificially overestimate residual heparin after protamine reversal in cardiac and vascular surgery.
- Pre-analytical vigilance: The crucial 60-minute centrifugation window to prevent Platelet Factor 4 (PF4) release and heparin neutralization.
- Analytical excellence: The power of two-step chromogenic assays with exogenous antithrombin. Featuring expert insights from Bruno Pougault (Global International Hemostasis Product Manager).
Listen now on Spotify.
Also streaming on Apple Podcasts on our channel Hemostasis Pulse!
How is your institution handling Anti-Xa reagent selection and pre-analytical sample turnaround?”
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