Hiteshi K.C. Chauhan: Why Mechanical Valve Thrombosis Is a Systems Failure, Not Just an Anticoagulation Error
Hiteshi K.C. Chauhan, Consultant, Department of Cardiology at Fortis Healthcare, shared a post on LinkedIn:
“We’ve all experienced this incredible moment in our clinical practice.
- A thrombosed mechanical mitral valve.
- Low-dose, slow-infusion thrombolysis.
- And then – the leaflets move again.
The tragedy: In LMICs, we see this more often than we would want to.
Thank you, Rheumatic Heart Disease.
For young patients receiving a mechanical valve, lifelong anticoagulation becomes essential.
Yet a study of 552 patients with RHD and mechanical valves found that only 27% of INR measurements were therapeutic, while 61% were subtherapeutic.
By year seven, INR testing had fallen to less than once a year.
Valve thrombosis is – therefore – not simply an anticoagulation failure. It is a systems failure surrounding a lifelong therapy.
We know what works:
- Reliable INR testing
- Affordable, consistent access to medication
- Continuity of care
- Long-term follow-up
The real challenge is implementation.
How do we make what works accessible at scale?
Case of low-dose, slow-infusion thrombolysis courtesy of JAMA Cardiology.”
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