Ney Carter Borges/LinkedIn
Apr 2, 2026, 16:08
Ney Carter Borges: Early Surgery vs Conservative Care in Asymptomatic Very Severe Aortic Stenosis
Ney Carter Borges, Member Cardiologist of Global Physician Association at Cleveland Clinic Florida, shared a post on LinkedIn:
”Early surgery vs conservative care in asymptomatic very severe aortic stenosis (10-year outcomes)
Key findings (Recovery Trial – 10-Year Follow-up)
Population:
Asymptomatic patients with very severe aortic stenosis
(AVA ≤0.75 cm², Vmax ≥4.5 m/s)
Primary Outcome (CV death or operative mortality):
- Early Surgery: 3%
- Conservative Care: 24%
- HR 0.10 (95% CI 0.02–0.43; p=0.002)
All-Cause Mortality:
- Early Surgery: 15%
- Conservative Care: 32%
- HR 0.42 (95% CI 0.21–0.86)
Heart Failure Hospitalization:
- Early Surgery: 0%
- Conservative Care: 19%
Number Needed to Treat (10 years):
- NNT ≈ 6 (CV death)
- NNT ≈ 7 (all-cause death)
Clinical interpretation
- Early intervention dramatically reduces cardiovascular mortality
- Benefit is sustained over 10 years (no curve convergence)
- Conservative strategy leads to:
- Delayed surgery
- Higher HF burden
- Increased pre-operative risk
- Key insight: ‘Waiting for symptoms may allow irreversible myocardial damage’
Practice-changing message
In carefully selected asymptomatic patients with very severe AS, early surgical AVR should be strongly considered, especially when:
- Low surgical risk
- High transvalvular velocity
- Evidence of disease progression.”

Other posts featuring Net Carter Borges on Hemostasis Today.
-
Jul 8, 2026, 14:17Maha Othman: Advancing Thrombosis and Hemostasis Research at ISTH 2026
-
Jul 8, 2026, 14:07Zain Khalpey: Atrial Fibrillation as the Hidden Driver of Preventable Ischemic Stroke
-
Jul 8, 2026, 11:33Ifeanyichukwu Ifechidere: Haemophilia A and B – From First Diagnosis to the Era of Gene Therapy
-
Jul 8, 2026, 10:29Bringing Hemophilia Care Closer to Communities in Togo – WFH
-
Jul 8, 2026, 10:12Natasha Jolakoski: Completing Advanced Training in Thrombosis and Hemostasis
-
Jul 8, 2026, 09:58Rola Ghasoub: Early Intracranial Hemorrhage Remains the Main Barrier to Cure in Acute Promyelocytic Leukemia
-
Jul 8, 2026, 05:53Excellent PhD Defense by Roberta Cirsmaru on Gene Therapy for Hemophilia A – CRH French Reference Center for Hemophilia Lyon
-
Jul 8, 2026, 05:48Riccardo Menandro: How Lipid Nanoparticles Are Shaping the Future of Rare Disease and Hemophilia Treatment
-
Jul 8, 2026, 05:39Daniel Victor Ortigoza: New Evidence from ATLANTIS-4D-CT on Apixaban and Subclinical Valve Thrombosis