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Rana Al-Hrout: Exploring Approach to Macrocytic Anemia
Oct 30, 2026, 05:11

Rana Al-Hrout: Exploring Approach to Macrocytic Anemia

Rana Al-Hrout, Clinical Pathology-Hematology Specialist at Ministry of Health – Jordan, shared a post on LinkedIn:

“Approach to Macrocytic Anemia

Macrocytic anemia is not a diagnosis by itself – it is a finding that requires a systematic diagnostic approach.

Key steps in the evaluation:

  1. Confirm macrocytosis (MCV more than 100 fL).
  2. Review the peripheral blood film and reticulocyte count.
  3. Distinguish between megaloblastic and non-megaloblastic causes.
  4. Assess vitamin B12 and folate levels when indicated.
  5. Consider liver disease, hypothyroidism, medications, hemolysis, and bone marrow disorders.”

Rana Al-Hrout

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