W. Alberto Sifuentes Giraldo: Non-Criteria Manifestations of Antiphospholipid Syndrome
W. Alberto Sifuentes Giraldo, Rheumatologist at Hospital Nuestra Señora de Sonsoles (Sacyl), shared a post on X, adding:
”Although the classification criteria for antiphospholipid syndrome (APS) classically require the presence of a thrombotic event in the venous vascular territory (e.g., deep vein thrombosis) or arterial territory (e.g., myocardial infarction, stroke), or recurrent fetal loss, this does not mean that patients with positive antiphospholipid antibodies who do not meet these criteria do not have this disorder.
The spectrum of APS manifestations is broad and encompasses several other symptoms that are not criteria, such as cutaneous manifestations including livedo reticularis, necrotic ulcers, pseudovasculitic lesions, digital gangrene, and splinter hemorrhages, among others.
The presence of antiphospholipid antibodies can also be associated with other symptoms, such as thrombocytopenia, valvular heart disease, epilepsy, or transverse myelitis. Furthermore, it carries an increased risk of other autoimmune disorders. In half of the cases, APS is associated with other autoimmune rheumatic diseases, the most frequent being systemic lupus erythematosus.
Non-Criteria Manifestations of Antiphospholipid Syndrome (APS). Adapted from: Pires da Rosa G, Espinosa G, Cervera R.
Non-criteria manifestations of antiphospholipid syndrome: an overview. Span J Med. 2021;1(2).”
Stay updated with Hemostasis Today.
-
Apr 29, 2026, 16:12Mavis Agnes Kisakye: Concluding a Successful Entrepreneurship Training for Our Mothers
-
Apr 29, 2026, 15:48Kriti Batni: Happy to Share on Our Chapter Being Published in Medicine Update 2026
-
Apr 29, 2026, 15:46Dima Shulkin: Comparing HALP and PIV for Mortality Prediction in ACS
-
Apr 29, 2026, 15:44Sonal Sonu: Securing First Prize in Research Oral Presentation at the CME
-
Apr 29, 2026, 15:43Andrew Shaw: Long COVID First Diagnostic Classification with 69% accuracy
-
Apr 29, 2026, 15:41Yazan Abou-Ismail: Contributing Evidence-Based Topic Review on the Evaluation of Easy Bruising
-
Apr 29, 2026, 15:36Mohamed Sherif Salem: Expanding the Role of Tenecteplase in Acute Ischemic Stroke
-
Apr 29, 2026, 15:31WFH Humanitarian Aid Program Reflects on a Result of Years of Consistent Work with AHTA – Yeolyan Hematology and Oncology Center
-
Apr 29, 2026, 15:29Behnood Bikdeli: A Landmark JACC Journals Issue on Pulmonary Embolism