William Aird/X
Sep 25, 2025, 05:56
William Aird: Why Does The PLASMIC Score For TTP Include A “Low” MCV?
William Aird, Professor of Medicine at Harvard Medical School, posted on X:
” 1/2
LOW MEAN CELL VOLUME AS MARKER OF TTP
Why does the PLASMIC score for TTP include a “low” MCV?
Because schistocytes are, by definition, smaller than mature RBCs → ↓MCV.
2/2
Why is the cutoff in the PLASMIC score <90 fL (not <80, which is lower limit of normal)?
Because the drop is modest (schistocytes are few vs intact RBCs) and because it’s partly offset by reticulocytosis (↑MCV).
Check out here.”
Stay updated with Hemostasis Today.
-
May 25, 2026, 05:25Abdullah Mohsin: Automated Detection of DVT Using Deep Learning and Doppler Ultrasound
-
May 25, 2026, 05:07The Dual Role of PAI-1 Mutations in Bleeding and Thrombotic Disorders – ICHCC
-
May 25, 2026, 05:04Fibrinogen αC Domain Lysines Drive Plasminogen Binding and Plasmin Generation – JTH
-
May 25, 2026, 04:50Gülşah Türkoğlu: An Encouraging Momentum Around the Adoption of Resolutions on Stroke Care at WHA79
-
May 25, 2026, 04:47Krishnakant Prasad: A Quick Clinical Review of Renal Papillary Necrosis
-
May 25, 2026, 04:40Rajiv Kumar Jain: World Health Assembly Adopts First-Ever Global Resolution on Stroke Prevention and Care
-
May 25, 2026, 04:23Sarfraz Ahmad: Diagnostic and Therapeutic Challenges in ICA Aneurysm Presenting With Epistaxis
-
May 24, 2026, 17:48Flora Peyvandi: Crucial Role of Placental ADAMTS13 in Perinatal Survival
-
May 24, 2026, 17:13Mahtab Mashayekhi: The Evolving Role of Red Blood Cell Exchange in the Management of SCD