Claire Auditeau: Thrilled to Share a Major Milestone From My PhD Journey!
Claire Auditeau, Medical Biologist – University Hospital Assistant at Greater Paris University Hospitals, shared on LinkedIn:
”Thrilled to share a major milestone from my PhD journey!
Our paper “Protein S Enhances the Phagocytosis of Phosphatidylserine-Exposing Erythrocytes: Implications in Sickle Cell Disease” has just been published in the American Journal of Hematology.
Our research has revealed that protein S significantly enhances the phagocytosis of phosphatidylserine-exposing erythrocytes and eryghosts.
This discovery is particularly significant for SCD patients, as we demonstrated that the accumulation of pro-coagulant and adherent eryghosts in circulation likely contributes to the pathogenesis of the disease.
These insights not only deepen our understanding of red blood cell clearance but also pave the way for exciting future therapeutic applications.
This four-year journey, at the crossroads of hemostasis and red blood cell biology, was made possible through a wonderful collaboration between HITh and BioTIGR.
Aurélie Fricot-Monsinjon, Camille Roussel, HITh lab, Inserm, Delphine Borgel, François Saller
Huge thanks to all co-authors and collaborators for their incredible teamwork and support throughout this project!
The article is available in open access.”
Read the full article here.
Article: Protein S Enhances the Phagocytosis of Phosphatidylserine-Exposing Erythrocytes: Implications in Sickle Cell Disease
Authors: Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel
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