Afshan Sumera: Plasma Proteomics Reveals Complement And Coagulation Disruption In Transfusion-Dependent Thalassemia
Afshan Sumera, Principal Lecturer in Medical Sciences at University of Lancashire, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Advances in Hematology, adding:
“I am pleased to share that my research article, ‘Proteomic Evidence of Complement and Coagulation Pathway Dysregulation in Transfusion-Dependent Thalassemia’, has been published in Advances in Hematology.
This study explored the plasma proteome of patients with transfusion-dependent thalassemia using LC-MS/MS proteomic analysis and identified significant alterations in complement and coagulation pathways.
This publication represents an important outcome of my PhD research journey and reflects years of work in study design, sample collection, laboratory analysis, data interpretation, manuscript preparation, and peer review.
I would like to express my sincere gratitude to my supervisors Prof Aziz Baba, Prof Ammu K Radhakrishnan and Prof Soon Keng Cheong, collaborators, and all patients and families who participated in this research. Their support and contributions made this work possible.
Citation: Sumera A., Radhakrishnan A.K., Baba A.A., Cheong S.K.”
Title: Proteomic Evidence of Complement and Coagulation Pathway Dysregulation in Transfusion-Dependent Thalassemia
Authors: Afshan Sumera, Ammu K. Radhakrishnan, Abdul Aziz Baba, Soon Keng Cheong

Stay updated with Hemostasis Today.
-
Jul 13, 2026, 16:01Advancing DIC Diagnosis in Cirrhosis Through Disease-Specific Risk Stratification – JTH
-
Jul 13, 2026, 15:52Joshua Muia: Presenting Our Research on ADAMTS13/VWF Dysregulation in Sepsis at ISTH 2026
-
Jul 13, 2026, 15:42Marc Carrier: Important New Data From the API-CAT Trial on Recurrent VTE During Extended Apixaban Therapy
-
Jul 13, 2026, 15:23Akshat Jain: 5 Key Clinical Takeaways from ISTH 2026
-
Jul 13, 2026, 15:15Alfonso J. Tafur: Insights on Periprocedural DOAC Management in Atrial Fibrillation at ISTH 2026
-
Jul 13, 2026, 14:42Bruno Pougault: The Global Momentum Behind Innovation in Thrombosis and Hemostasis
-
Jul 13, 2026, 14:34Julie Vassart: Optimizing DOAC Detection in an Evolving Anticoagulant Landscape at ISTH 2026
-
Jul 13, 2026, 13:57Heghine Khachatryan: The Diagnostic Dilemma of Non-Criteria Obstetric APS
-
Jul 13, 2026, 13:49Mitra Najafi: Translating Years of Innovation into Global Scientific Dialogue at ISTH 2026