Andrés Felipe Escobar González: Inno8 – Bringing Oral Innovation to Haemophilia Care
Andrés Felipe Escobar González, Pediatric Hematologist, Hemophilia Program at Medicarte, shared a post on LinkedIn about a recent article by Jacob Lund et al., published in Blood, adding:
“The development of Inno8, an orally administered factor VIIIa-mimetic antibody fragment, represents an exciting step toward transforming hemophilia A treatment.
An oral therapy capable of mimicking FVIIIa function could offer a more convenient, non-intravenous approach to restoring coagulation and potentially reducing treatment burden.
The key will be translating this innovative concept into robust clinical efficacy, safety, and long-term protection against bleeding.
Innovation in hemophilia care means not only improving hemostasis, but also making effective treatment more accessible and patient-centered.”
Title: Development of Inno8, an orally administered factor VIIIa-mimetic antibody fragment for treatment of hemophilia A
Authors: Jacob Lund, Jais Rose Bjelke, Daniele Granata, Thomas Egebjerg, Pierre-Louis Bardonnet, Zoey Wang Zhuoran, Eva Johansson, Bjarne Rask Poulsen, Jakob Borre Dahl Nissen, Philip Jonas Sassene, Per Franklin Nielsen, Lars Jørgensen, Mads Bjelke, Pingping Chen, Sr., Esther Bloem, Mette Loftager, Kasper Lamberth, Katharina L. Kopp, Helle Demuth, Per-Olof Wahlund, Mie Mandal Mortensen, Birgitte Nissen, Mahdieh Dagina Pedersen, Emma Balantic-Nielsen, Michael Monrad Grandal, Anne Westall, Andreas Vegge
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