TNFα Role in Body’s Recovery from Anemia of Inflammation
Stefano Rivella, Leader of the RNA Gene Therapeutics group of The Penn Institute for RNA Innovation, shared a post on LinkedIn:
In a preclinical study, researchers at the Children’s Hospital of Philadelphia discovered that the cytokine tumor necrosis factor alpha (TNFα) plays a key role in aiding the body’s recovery from anemia of inflammation (AI), a blood disorder that can develop following chronic illness or infection.
The study was led by Dr. Amaliris Guerra, a former NIH T32 and Diversity Supplement Postdoctoral Trainee, CHOP Bridge to Faculty Fellow, and NIH Early-Stage Investigator Diversity Supplement Trainee, with co-authorship from Stefano Rivella, PhD, Kwame Ohene-Frempong Endowed Chair in Pediatric Hematology at CHOP.
Read Lauren Ingeno exploring the objectives.
Study: TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed Brucella Abortus
Authors: Vania Lo Presti, Ding-wen Chen, Ana Martins, Pankaj Sharma, Yelena Ginzburg, Carlo Castruccio Castracani, Carla Casu, Ritama Gupta, Raffaella Gozzelino, Edward Behrens, Laura F Bennett, Robert Paulson, Peter Kurre, Stefano Rivella, Amaliris Guerra
Stay updated on the latest scientific advances in Hematology with Hemostasis Today.
-
Sep 16, 2026, 16:06Katrina Louise Manalaysay: In Your 20s, You Might be Given the Opportunity to Donate Blood for the First Time
-
Sep 16, 2026, 15:45Matthew Hazell: A Brilliant Explanation of Phenotype vs Genotype Using a LEGO House
-
Sep 16, 2026, 15:23Ahmad Al-Ramahi: Presenting the Military Pharmacists Blood Training Course at the FIP World Congress
-
Sep 16, 2026, 15:21HIT Reimagined: Can 12-Lipoxygenase Inhibition Stop Immune Thrombosis?
-
Sep 16, 2026, 14:42Ruchi Punamia: Beyond the Blood Bank and The Clinical Impact of Apheresis
-
Sep 16, 2026, 14:06Kalyan Roy: Celebrating Apheresis, Advancing Care, Saving Lives
-
Sep 16, 2026, 13:38Andrew Zapfel: Advancing Sickle Cell Disease Care and Research
-
Sep 16, 2026, 13:30Thirunavukkarasu Angappan: Why Plasma-Derived Factor VIII Still Matters for Inhibitor Patients
-
Sep 16, 2026, 13:22Matthew Hazell: New BSH Guidance for Fetal, Neonatal and Paediatric Transfusion