Carmine Siniscalchi/LinkedIn, Pierpaolo Di Micco/FADOI - Scientific Society of Internal Medicine
Sep 22, 2026, 18:37
Carmine Siniscalchi: Age-Adjusted D-Dimer Cutoffs in DVT Diagnosis
Carmine Siniscalchi, Associate Professor of Internal Medicine under the Italian National Scientific Qualification (ASN), shared a post on LinkedIn about a recent article he and Pierpaolo Di Micco co-authored, published in JAMA, adding:
”Pleased to share our Letter to the Editor discussing the ADJUST-DVT study and the clinical implications of age-adjusted D-dimer cutoffs for ruling out deep vein thrombosis.
We highlight some still-open questions regarding generalizability, assay variability, distal DVT, recurrent VTE, and translation into real-world clinical practice.”
Title: Age-Adjusted D-Dimer Cutoffs to Exclude DVT
Authors: Carmine Siniscalchi and Pierpaolo Di Micco

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