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Filippo Crea: Exploring the Role of PAR4 in Platelet Hyperactivation in Hypertension
Sep 6, 2026, 14:12

Filippo Crea: Exploring the Role of PAR4 in Platelet Hyperactivation in Hypertension

Filippo Crea, Editor-in-Chief of European Heart Journal, shared a post on X about a recent article by Mingzhu Wang et al. published in European Heart Journal, adding:

Hypertensive patients exhibit heightened susceptibility to pro-thrombotic state.

New study explores protease-activated receptor 4 (PAR4) on platelet hyperactivation in hypertension.”

Title: Angiotensin II-driven TGF-β1 increases platelet PAR4 expression enhancing thrombotic risk in hypertension

Authors: Mingzhu Wang, Zixian Liu, Yufei Chen, Shufang Wang, Yongbo Ma, Jiaorui Wang, Ke Zheng, Mingjie Li, Meiling Wu, Zhichao Fan, Yunfeng Chen, Dongchao Lu, Jian Li, Haidong Guo, Deyu Fu, Liang Hu

Filippo Crea

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