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Nathan Connell: New Research on Heavy Menstrual Bleeding in Women With von Willebrand Disease
Nathan Connell/LinkedIn
Sep 22, 2025, 12:46

Nathan Connell: New Research on Heavy Menstrual Bleeding in Women With von Willebrand Disease

Nathan Connell, Clinical Chief of Hematology at Brigham and Women’s Faulkner Hospital, shared on LinkedIn:

“New research on heavy menstrual bleeding in women with von Willebrand disease

This open-access article in Haemophilia Journal focuses on heavy menstrual bleeding (HMB) in women with von Willebrand disease.

While VWD is the most common inherited bleeding disorder, its impact on women’s health, particularly HMB, is often underdiagnosed. This research is a crucial reminder of the importance of considering underlying bleeding disorders in women presenting with HMB.

Key takeaways from the article and related research:

  • HMB is a highly prevalent symptom in women with VWD, affecting a significant majority of patients.
  • The article reinforces that HMB in women with VWD can lead to complications such as iron deficiency anemia, which severely impacts a person’s quality of life.
  • Diagnosis can be challenging as VWF levels can fluctuate. The article stresses the importance of proper hemostatic testing and a detailed patient history to avoid misdiagnosis.
  • Effective management strategies for HMB in women with VWD are discussed, including hormonal therapies, antifibrinolytic drugs, and in some cases, VWF/FVIII concentrate.

This is a vital topic for hematologists, gynecologists, and primary care physicians to collaborate on, ensuring women receive the correct diagnosis and treatment.”

Title: Prevalence and Impact of Heavy Menstrual Bleeding in Women With von Willebrand Disease Across Age Groups: A Retrospective Study

Authors: Anna Olsson, Petra Elfvinge, Eva Zetterberg, Linda Myrin-Westesson

Heavy Menstrual Bleeding

Read the full paper here.

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Anna Olsson bleeding disorders Eva Zetterberg Haemophilia journal Headlines Health heavy menstrual bleeding Hematology Hemostasis Hemostasis Today Iron-Deficiency Anemia Linda Myrin-Westesson Medicine Nathan Connell Petra Elfvinge Retrospective Study Von Willebrand Disease Women with Bleeding Disorders
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