Tessa Jaspers and Colleagues on Current Evidence Not Supporting Routine Anti-Xa Monitoring in Use of LMWH
Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn:
”A systematic review on anti-Xa monitoring in the therapeutic use of low-molecular-weight heparins
LMWHs are widely used in diverse patient groups (renal impairment, pregnancy, obesity), but the value of anti-Xa monitoring remains unclear.
This systematic review of 48 studies (RCTs and observational) found:
- Comparable bleeding and VTE rates in monitored vs. unmonitored patients.
- Frequent dose adjustments in monitored cohorts.
- Weak or absent correlation between anti-Xa levels and clinical outcomes.
Current evidence does not support routine anti-Xa monitoring for LMWH dose adjustment.”
Read the full paper in JTH.
Article: A systematic review on anti-Xa monitoring in the therapeutic use of low-molecular-weight heparins
Authors: Tessa C. C. Jaspers, P. Christian Remmelzwaal, Eefje P.S. Weersink, Karina Meijer, Nakisa Khorsand
Stay updated on all science in the field of anticoagulation with Hemostasis Today.
-
Dec 7, 2025, 18:43ASH25 Day 2: Don’t Miss The Highlights
-
Dec 7, 2025, 17:01Abdul Mannan: How Do You Manage a Major Surgery When Blood Transfusion is Impossible?
-
Dec 7, 2025, 16:51Ahmed Bahi on Lina Merghani’s Critique of Early Withdrawal of Aspirin after PCI
-
Dec 7, 2025, 16:30Eloïse Laouenan Presents the Results of HEMOTHEPP-CHU Brest-GETBO Prospective Study
-
Dec 7, 2025, 16:21Jonathan Douxfils: Can We Estimate the VTE Risk of a Pill Before a Million Women Use It?
-
Dec 7, 2025, 16:06Pablo Corral on Why Early LDL-C Reduction Saves Lives
-
Dec 7, 2025, 15:53Paul Batty Congratulates Giulia Simini on Taking The Joint BSH-ASH Abstract Award
-
Dec 7, 2025, 15:35Federica Fogacci Presents The New ILEP Consensus Paper
-
Dec 7, 2025, 15:20Deep Molecular Modeling for Type 2A VWD from Omid Seidizadeh