Manuel Requena: Cherrypicking Inclusion in Clinical Trials May Underestimate The Effect of An Intervention
Manuel Requena, Interventional Neurologist at Vall d’Hebron Barcelona Hospital Campus, shared in LinkedIn:
”Cherrypicking inclusion in clinical trials may underestimate the effect of an intervention.
Two centers involved in DMVO clinical trials have compared those patients included in trials and those that were treated without randomization during recruitment period (no exclusion criteria).
Patients included in clinical trials had lower median NIHSS score and smaller hypoperfunded area.
Those results (and recent guidelines) highlight the relevance of consecutive enrollment.
PS: Proud of the contribution of our resident Ane Murillo as first author.”
Read the full article here.
Article: Endovascular Treatment for Medium and Distal Vessel Occlusion Stroke: Are We Missing the Point?
Authors: Ane Murillo-Olaizola; Marc Rodrigo-Gisbert; Manuel Requena; Anderson Brito-Alvarado; Francesco Diana; Marta de Dios Lascuevas; Marta Olivé-Gadea; Jordi Mayol; Álvaro García-Tornel; Eric Kontowicz; Mario Zanaty; Jorge Cespedes; William D. Haselden; Leonardo Cruz-Criollo; Nashwa Abdelhakim; Renato Simonetti; Federica Rizzo; David Hernández; Alejandro Tomasello; Santiago Ortega-Gutierrez; Marc Ribo
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