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Marta Velia Antonini: Incidence and Outcomes of ECMO Circuit Failure in Children
Sep 12, 2026, 13:53

Marta Velia Antonini: Incidence and Outcomes of ECMO Circuit Failure in Children

Marta Velia Antonini, Hematologist, Perfusionist ECMO and NRP Specialist and Chair of the Normothermic Regional Perfusion EuroELSO Working Group, shared a post on X about a recent article she and her colleagues co-authored, published in ASAIO Journal, adding:

“Circuit thrombosis and mechanical failure in children in ECMO analysis of the ELSO Registry, 2020 – 2024 higher than 20K pts low than 18 years: higher than21K runs/ higher than26K circuits circuit failure is equal to complication requiring circuit or component replacement circuit failure common: 19.2% circuits, at least one replacement in 15.3% of runs median time to failure 129.5 hours neonatal age, low weight (low than 3 kg,) higher center volume, VA configuration, prior circuit failure associated with increased risk failure associated with significantly increased mortality (49% vs 34%), strongest effect in neonates.”

Title: Time to Pediatric Extracorporeal Membrane Oxygenation Circuit Failure: An Extracorporeal Life Support Organization Registry-Based Study

Authors: Adrian C Mattke, Kerry E Johnson, Supreet Marathe, Nelson Alphonso, Sarfaraz N Rahiman, Nitesh Singhal, Alexander D Hussey, Craig A McBride, Antje Blumenthal, Giles J Peek, Mari Takashima

Marta Velia Antonini

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