Prashant Mehta: Optimizing Inotuzumab Dosing in B-ALL
Prashant Mehta, Senior Consultant and Program Head at Amrita Hospital Faridabad, shared a post on LinkedIn:
“I have immense respect for Leukemia Department – Hagop Kantarjian, M.D.
We look upto him as one of the top leukemia researchers in the world .
Today I was so glad to get a citation alert for our group’s real world study on efficacy and toxicity of lower doses Inotuzumab from Amrita Hospital, Faridabad from Dr Kantarjian’s paper .
We were able to demonstrate a similar efficacy and lower toxicity of lower doses of in relapsed or refractory B-ALL in a small cohort of 15 patients.
Dr Kantarjian’s paper on dose optimization of Inotuzumab is very important to us and his citation of our study in his review inspires us immensely to keep looking for better answers for our patients together.
Saphalta Baghmar Vidit Kapoor Dr Pravas Mishra MD DM Nupur Das Moushumi Suryavanshi Swati Pabbi Rahul Katharia
Thank you so much Dr Nitin Jain for his continued academic endeavors for India which have been instrumental in our efforts to optimize Inotuzumab dose at our centre .
We will need to do a lot more in India to understand optimal dose for our patients considering a very high prevalence of fatty liver , higher vulnerability to SOS or VOD , lower body mass or sarcopenia and metabolic factors.”
Title 1: Dose Optimization of Inotuzumab Ozogamicin in Adult Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia
Authors: Daniel J. DeAngelo, Ying Chen, Ryan D Cassaday, Jennifer Hibma
Title 2: Real-world experience with inotuzumab ozogamicin in high-risk and R/R B-cell acute lymphoblastic leukemia.
Authors: Anshul Jain, Prashant Mehta, Jagsahib Kaur, Vidit Kapoor, Pravas Chandra Mishra, Saphalta Baghmar, Moushumi Suryavanshi, Nupur Das, Rahul Kumar, Swati Pabbi, Kusum Gupta, Ankita Singh
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