Teagan Prouse and Colleagues on Alternate Functions of Physiological Anticoagulants
Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn:
”Alternate functions of physiological anticoagulants
By Teagan Prouse, Alan Mast, Vera Ignjatović, Mirjana Kovac, Bereczky Zsuzsanna, and Rinku Majumder
Classical anticoagulants—antithrombin, protein C, protein S, and tissue factor pathway inhibitor (TFPI)—are known for maintaining hemostatic balance.
Yet emerging research reveals far broader physiological roles beyond coagulation control.
Insight: These anticoagulants act as multifunctional modulators of inflammation, immunity, angiogenesis, and barrier integrity, highlighting therapeutic opportunities that extend well beyond thrombosis—toward truly pleiotropic vascular medicine.”
Read the full article in JTH.
Article: Alternate functions of physiological anticoagulants
Authors: Teagan Prouse, Alan E. Mast, Vera Ignjatovic, Mirjana Kovac, Zsuzsanna Bereczky, Rinku Majumder
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