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Vascular Damage from Pancreatic Juice Leakage
Giovanni Marchegiani/X
Aug 11, 2025, 13:50

Vascular Damage from Pancreatic Juice Leakage

Giovanni Marchegiani, MD, Pancreas Surgeon at the University of Padova, shared on X:

”Pancreatic juice leakage
Mechanisms of histopathologic vascular damage

Activation of pancreatic proteases by intestinal fluids

Histologic damage to arterial media lead to aneurysm formation

Role for administration of protease inhibitors.”

Read the full article in Surgery.

Title: Mechanisms of histopathologic vascular damage caused by pancreatic juice leakage: Implications for preventing hemorrhagic complications

Authors: Yusuke Seki, Takeaki Ishizawa, Kento Mitsuhashi, Natsuko F. Inagaki, Kazuhiro Mori, Genki Watanabe,  Toru Komatsu, Yasuteru Urano, Hiroyuki Abe, Tetsuo Ushiku, Taichi Ito, Kiyoshi Hasegawa

 

Vascular

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Aneurysm Genki Watanabe Giovanni Marchegiani Health Hematology Hemostasis Today Hiroyuki Abe Histologic Damage Kazuhiro Mori Kento Mitsuhashi Kiyoshi Hasegawa Medicine Natsuko F. Inagaki Pancreatic juice leakage pancreatic proteases Surgery Taichi Ito Takeaki Ishizawa Tetsuo Ushiku Toru Komatsu Vascular Damage Yasuteru Urano Yusuke Seki
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