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Morten Haugen Warns of IgG Risks for High-Frequency Plasma Donors
Morten Haugen/LinkedIn
Sep 19, 2025, 16:48

Morten Haugen Warns of IgG Risks for High-Frequency Plasma Donors

Morten Haugen, Resident physician specializing in immunology and transfusion medicine at Oslo University Hospital, shared a post on LinkedIn:

“New evidence on plasma donation frequency:

  • The first paper from my PhD-work is now published in Vox Sanguinis! In this randomized trial we found that
    High-frequency (3×/2 weeks) and regular-frequency (1×/2 weeks) plasma donation significantly lowered total serum protein and immunoglobulin G.
  • Up to 26% of high-frequency donors dropped below the IgG safety threshold of 6.0 g/L, even when starting with normal levels of more than 8.0 g/L in most donors.
  • Many plasma proteins had not recovered 4 weeks after the last donation.

These findings highlight the need for careful donor monitoring and further research into long-term health effects.

Full article here

Morten Haugen Warns of IgG Risks for High-Frequency Plasma Donors

Thanks to the volunteer blood donors, the research team and my co-authors Karin Magnussen, Tor Strand and Lise Sofie Nissen-Meyer for making the study possible.”

Stay updated with Hemostasis Today.

Clinical Research Donor Risk Health Hematology Hemostasis Hemostasis Today High-Frequency Plasma Donors IgG Karin Magnussen Lise Sofie Nissen-Meyer Medicine Morten Haugen Tor Strand
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