Irma Bagdoniene: Lowering LDL May Alter Inflammatory and Oxidative Pathways
Irma Bagdoniene, Cardiologist and Lipidologist at Klinikum Lippe – University Hospital for Cardiology, Angiology, and Internal Intensive Care Medicine, posted on LinkedIn:
“Lowering lipids — but increasing oxidation?
A new study by Koutsogianni et al. (2025) looked at people with high Lp(a) and found something unexpected:
– Statins and ezetimibe raised oxidized phospholipids on apoB and apo(a), reduced those on plasminogen,
– while PCSK9 inhibitors had no clear effect.
So even when we lower LDL cholesterol, other inflammatory and oxidative processes may change in ways we don’t yet understand.
The message is clear: we need more studies to understand how lipid-lowering therapies truly affect the biology of Lp(a).”
Title: Effect of lipid-lowering medications on oxidized phospholipids in individuals with elevated LIPOPROTEIN(a)
Authors: Amalia Despoina Koutsogianni, Fotios Barkas, Constantinos Tellis, Alexandros Tselepis, George Liamis, Sotirios Tsimikas, Evangelos Liberopoulos
Read full article here.
Stay updated with Hemostasis Today.
-
Sep 21, 2026, 15:56Anita Zaidi: Why Only 2% of Health Research and Development Goes to Women’s Conditions
-
Sep 21, 2026, 15:49Omid Khalafi: Gating Strategy and How Do We Decide Which Cells to Analyze
-
Sep 21, 2026, 15:44Levacetylleucine: A New Therapeutic Approach to Ataxia Telangiectasia
-
Sep 21, 2026, 15:40Andreas Tridimas: The Diagnostic Traps of Lipaemic Blood – Why a Normal Amylase Can Mislead You
-
Sep 21, 2026, 15:33Arsene Mekinian: Exploring Cardiac Involvement in Behçet’s Disease
-
Sep 21, 2026, 15:23Anis Mahjoubi: MRI Findings of Krukenberg Tumors
-
Sep 21, 2026, 15:08Fikreab Tesfaye Tefera: 10 Practical Take-Home Points for Diagnosing Iron Deficiency Anemia
-
Sep 21, 2026, 14:10Aswin K Mohan: Lessons from TRANSCON 2026 – Building Resilient Blood Supply Systems Before Crisis Hits
-
Sep 21, 2026, 14:00Vincent Lu: Beyond PT and aPTT – How Hemostasis Evolves Across a Lifetime