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Charles Greenberg: Hematology Has Always Been at the Heart of Medical Discovery
Charles Greenberg/LinkedIn
Nov 16, 2025, 05:09

Charles Greenberg: Hematology Has Always Been at the Heart of Medical Discovery

Charles Greenberg, Professor of Medicine at Medical University of South Carolina, shared a post on LinkedIn:

“Hematology has always been at the heart of medical discovery. Systems-Based Hematology can ensure it remains central to how we deliver smarter, safer, and more sustainable care.

⸻

Systems-Based Hematology: Protecting a Discipline at Risk

Academic hematology is approaching an inflection point.
As research funding tightens, RVU-based compensation expands, and fewer trainees enter benign (“classical”) hematology, one of the most intellectually rigorous and discovery-driven fields in medicine is slowly being squeezed toward extinction.

And yet—no specialty has a broader systems impact.
Bleeding. Thrombosis. Transfusion. Cytopenias. Diagnostic stewardship. Rare diseases. Laboratory pathways. Every major hospital depends on this expertise, whether they realize it or not.

If classical hematology disappears, so does a century of evidence-based innovation that built modern medicine.

The path forward is clear: Systems-Based Hematology (SBH).

SBH embeds hematologists within the health system, empowering them to:

  • Lead cost-saving stewardship programs (HIT, anticoagulation, transfusion, peri-procedural management)
  • Guide rational testing and laboratory utilization
  • Improve patient safety and reduce complications
  • Develop clinical pathways for thrombosis, bleeding, and rare hematologic diseases
  • Maintain an academic mission linking discovery, clinical trials, and implementation science

SBH is not a replacement for classical hematology—it is the strategy that keeps it alive.

But it requires institutional investment:
protected time, dedicated roles, support from deans and health-system leadership, and recognition that RVUs alone cannot define the value of a thinking discipline.

If academic centers choose not to support this model, benign hematology will continue to erode, leaving hospitals without the expertise needed to manage complex bleeding and thrombosis issues, rising drug costs, and expanding diagnostic complexity.

If we act now, Systems-Based Hematology can usher in a new era of stewardship, discovery, and quality improvement across entire health systems.

If we do nothing—an irreplaceable discipline will quietly fade.

The future of hematology depends on systems-based thinking.”

Stay informed with Hemostasis Today.

Academic Medicine bleeding Charles Greenberg cytopenias Diagnostic stewardship Health Health Systems Hematology Hemostasis Hemostasis Today Laboratory pathways Medicine Rare Diseases thrombosis transfusion
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