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Susan Goobie: Pediatric Transfusion Rates and Risks Spike
Nov 22, 2025, 13:56

Susan Goobie: Pediatric Transfusion Rates and Risks Spike

Susan Goobie, Pediatric Anesthesiologist at Boston Children’s Hospital, posted on LinkedIn:

”Our BJA Transfusion Outcomes in Paediatric Surgical Patients (TOPS) study reports that perioperative paediatric red blood cell transfusion trended upward over the past decade, with an overall transfusion rate of 6.3% and of 13.3% in neonates.

The 30-day mortality rate in those transfused was 2.4%, and was 14.9% in neonates, compared with 0.2% in the non-transfusion group.

We report an overall 1.2- to 5.2-fold increased rate of morbidity and 2-fold increased rate of mortality in the cohort exposed to RBC transfusion perioperatively compared with the cohort who did not receive blood.

Which surgical procedures associated with the highest probability of blood transfusion?
Is there an increased risk of infection in the transfused patients?
Does the total transfusion volume matter?
How can patient blood management be used to decrease transfusion exposure in neonates, children and adolescents?

Read our article – free to download for 50 days.”

Title: Transfusion and outcomes in paediatric surgical patients: an 11-year retrospective North American cohort study

Authors: Susan Goobie, David Faraoni

Susan Goobie

 

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