Tassos Grammatikopoulos and Colleagues Share: The Immunological Profile of Children With Portal Hypertension
Tassos Grammatikopoulos, Medical Trustee at The British Liver Trust, shared a post on LinkedIn:
“We are excited to share our latest publication in Digestive and Liver Disease: “The immunological profile of children with portal hypertension”.
Portal hypertension affects thousands of children worldwide, yet diagnosis remains invasive and treatment options are limited. Our comprehensive review examines how immune dysregulation—including altered cytokine profiles, T cell dysfunction, and inflammatory responses—drives disease progression in conditions such as biliary atresia and portal vein thrombosis. By understanding these immune mechanisms, we’re identifying potential non-invasive biomarkers and novel therapeutic targets beyond liver transplantation.
Read the full open-access article:”
Title: The immunological profile of children with portal hypertension
Authors: Fabiola Di Dato, Raffaele Iorio, Eirini Kyrana, Yun Ma, Tassos Grammatikopoulos

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