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Shiny K. Kajal: A Hidden Cause of Persistent Mild Anemia
Shiny K. Kajal/LinkedIn
Feb 8, 2026, 12:57

Shiny K. Kajal: A Hidden Cause of Persistent Mild Anemia

Shiny K. Kajal, Senior Resident at Adesh University, shared a post on LinkedIn:

“Silent Hemoglobin Variants: A Hidden Cause of Persistent Mild Anemia

Persistently low or borderline hemoglobin (often 9–11 g/dL) is not always nutritional anemia.

A significant proportion of individuals are heterozygous carriers of hemoglobin variants (Hb E, Hb D Punjab, Hb Lepore, β-thalassemia trait, sickle cell trait) and remain clinically asymptomatic.

These carriers:

  • Have mild or no anemia
  • Lead normal lives
  • Are frequently misdiagnosed as iron deficiency and overtreated

The real risk emerges when two carriers marry, leading to severe hemoglobinopathies in offspring.

HPLC hemoglobin analysis is the preferred first-line screening tool for:

  • Structural variants
  • Quantitative disorders
  • Premarital and antenatal screening

Key message:

Genetic screening and counseling prevent disease burden—horoscope matching does not.

Match hemoglobin before matching horoscopes.”

Shiny K. Kajal: A Hidden Cause of Persistent Mild Anemia

More posts from Shiny K. Kajal on Hemostasis Today.

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