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March, 2026
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Philip Wenzel: The Role of MyD88 in the Inflammatory Transition from Hypertension to Heart Failure
Mar 11, 2026, 13:04

Philip Wenzel: The Role of MyD88 in the Inflammatory Transition from Hypertension to Heart Failure

Philip Wenzel, Director of the Medical Clinic I, Darmstadt Hospital, shared a post on LinkedIn about a recent article he and his colleagues co-authored, adding:

“After so many years in the making, our paper is finally out!

Very proud to have it published as editor’s choice in EHJOpen… starting off as Sabine’s PhD thesis, it evolved into a truely translational project spanning from genetic mouse models to a GWAS of 15y follow-up to pinpoint the role of MyD88 for the inflammatory transition from Hypertension to Heart Failure.

Enjoy the read!”

Title: MyD88 in myeloid cells drives angiotensin II-induced vascular inflammation, is associated with prevalent heart failure and predicts all-cause mortality in arterial hypertension

Authors: Sabine Wild, Stefanie Finger, Andreas Schulz, Melania Aluia, Jimena Bravo, Rahul Kumar, Jeremy Lagrange, Gregorio Alanis-Lobato, Voahanginirina Randriamboavonjy, Johannes Wild, Michael Molitor, Christian Müller, Tanja Zeller, Alexander Gieswinkel, Andreas Daiber, Susanne Karbach, Marcus Dörr, Ingrid Fleming, Philipp Lurz, Thomas Münzel, Markus Radsak, Katrin Schäfer, Daniela S Krause, Miguel A Andrade-Navarro, Philipp Wild, Philip Wenzel

 Read the Full Article on European Heart Journal Open

Philip Wenzel

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