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Jay Herath: Fitusiran Advancing Hemophilia Care Beyond Factor Replacement
Mar 24, 2026, 02:50

Jay Herath: Fitusiran Advancing Hemophilia Care Beyond Factor Replacement

Jay Herath, Professor of the Practice at Loyola University, shared a post on LinkedIn:

Qfitlia (fitusiran), approved in 2025, is a first-in-class siRNA therapy that treats hemophilia A and B by targeting antithrombin-III mRNA in the liver.

Instead of replacing missing clotting factors (Factor VIII or IX), it reduces antithrombin levels, restoring the body’s ability to generate thrombin and form stable blood clots.”

Jay Herath

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