A Self-Regulatory Mechanism of The PolyP-Thrombin-Fibrin Complex – JTH
Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Xintong Yao et al, adding:
”Formation of a Ternary Polyphosphate-Thrombin-Fibrin Complex Attenuates Thrombin Activity
Platelet-released polyphosphate, like heparin, promotes formation of a ternary polyP-thrombin-fibrin complex that simultaneously protects clot-bound thrombin from antithrombin inhibition while reducing its capacity to generate new fibrin, revealing a novel self-regulatory mechanism in coagulation.”
Title: Formation of a ternary polyphosphate-thrombin-fibrin complex attenuates thrombin activity
Authors: Xintong Yao, James C. Fredenburgh, Jeffrey I. Weitz
Read the Full Article on JTH
Stay updated on all scientific advances with Hemostasis Today.
-
May 27, 2026, 17:51Nita Radhakrishnan: Post Graduate Institute of Child Health Receives WFH Data Quality Certification for Excellence
-
May 27, 2026, 17:51Fiona Robinson: What exactly Are Rebalancing Agents for Bleeding Aisorders?
-
May 27, 2026, 17:14Khurram Nasir: Can Earlier LDL-C Lowering Change the Trajectory of Cardiovascular Disease?
-
May 27, 2026, 17:09Yvonne Jongejan: Allele-Selective Silencing Therapy for VWD and Thrombotic Disorders
-
May 27, 2026, 16:58Catherine Moran: Important Step Forward as 1st WHO Resolution on Stroke Gets Adopted at WHA79
-
May 27, 2026, 16:08Heghine Khachatryan: Thrombosis in Oncology Remains a Major Healthcare Burden
-
May 27, 2026, 16:00Revealing Critical Gaps in Hemophilia Diagnosis and Access to Care in India – WFH
-
May 27, 2026, 16:00Melissa Hollo: Women Deserve Proactive Care, Not Reactive Care
-
May 27, 2026, 15:59Piotr Czempik: First Report of ROTEM Findings in Triple-Positive APS and Hageman Anomaly