Andrew Aswani: How NETs Contribute to Disease and Why They Matter
Andrew Aswani, Co-Founder, Chief Medical Officer at Santersus AG shared a post on LinkedIn about a recent article by Michal Santocki and Elzbieta Kolaczkowska, published in Cells:
”The growing body of research on neutrophil extracellular traps (NETs) continues to reshape our understanding of inflammation, immunity, and thrombosis.
This 2020 foundational MDPI review on immune‑complex-induced NETosis highlights that NETs are not just byproducts of inflammation-they are active drivers of vascular injury, coagulation, and organ dysfunction.
When NETs accumulate unchecked, they create a cascade of endothelial damage, platelet activation, and immune dysregulation that underpins some of the most severe conditions we face-sepsis, autoimmune disease, cancer, and cardiovascular complications.
At Santersus AG, we’re working to help clinicians intervene at this root cause. Our NucleoCapture platform is designed to selectively remove NETs from circulation, offering a targeted, extracorporeal approach that avoids the systemic side effects of many pharmacologic therapies. As the scientific community continues to validate the central role of NETs in immune‑driven thrombosis, the need for NET‑focused interventions becomes even more urgent.
This research strengthens the case for a new therapeutic paradigm-one that doesn’t just modulate inflammation, but directly removes the molecular drivers of immune‑mediated injury.”
Title: On Neutrophil Extracellular Trap (NET) Removal: What We Know Thus Far and Why So Little
Authors: Michal Santocki, Elzbieta Kolaczkowska
Stay updated on all scientific advances with Hemostasis Today.
-
Oct 20, 2026, 15:04Laura S.: Could Speaking Up Prevent Maternal Deaths from Thrombosis?
-
Oct 20, 2026, 14:44Pete Stibbs: VTE in Professional Athletes – When Fitness Is Not Enough
-
Oct 20, 2026, 14:39Jan Hartmann: How Hemophilia Care Has Advanced Over the Past Decade
-
Oct 20, 2026, 14:27Amna Jamalallail: SCD and Thalassemia in Jeddah – A Public Health Perspective
-
Oct 20, 2026, 14:14Advancing Thalassaemia and Sickle Cell Care Through Nordic Collaboration – TIF
-
Oct 20, 2026, 14:01Ashkan Forouzani։ Warfarin or DOACs in Protein C and S Deficiency?
-
Oct 20, 2026, 13:20The Global Blood Crisis – Are We Solving the Wrong Problem?
-
Oct 20, 2026, 06:45Grant Garcia: Why Does a Blood Clot Diagnosis Immediately End an Athlete’s Season?
-
Oct 20, 2026, 06:35Parag Tamhankar: Landmark Study Reveals Genetic Spectrum and Targeted Therapies for ALPS in the Indian Population