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Tushar Pandey: When Low Platelets Are Not ITP
Tushar Pandey/LinkedIn
Apr 27, 2026, 14:31

Tushar Pandey: When Low Platelets Are Not ITP

Tushar Pandey, Director and Head of Raghav Institute of Hematology, Hemato-Oncology and BMT at Raghav Healthcare, Editorial Board Member at Journal of Cancer Chemotherapy, Program Director of Hemato – Oncology at International Association For Integrated Oncology, shared a post on LinkedIn:

”When to suspect ITP, TTP, HIT and VITT – a clinical priority

Thrombocytopenia is common…

But not all low platelets are ITP.

Early recognition can be life-saving.

Think beyond ITP

ITP (Immune Thrombocytopenia)

  • Isolated low platelets
  • Mucocutaneous bleeding
  • Normal Hb and WBC

TTP (Thrombotic Thrombocytopenic Purpura)

  • Thrombocytopenia plus MAHA
  • Neurological symptoms
  • Renal involvement

Hematological emergency

HIT (Heparin Induced Thrombocytopenia)

  • Platelet fall more than 50%
  • 5–14 days after heparin
  • Thrombosis present

VITT (Vaccine Induced Thrombotic Thrombocytopenia)

  • 5–30 days post vaccination
  • Unusual thrombosis (CVST, splanchnic)
  • High D-dimer

Key takeaway

Low platelets are not all the same
Missing these diagnoses can be fatal

Clinical rule

Thrombocytopenia plus

  • Hemolysis
  • Thrombosis
  • Neurologic symptoms
  • Drug / vaccine history

Think TTP / HIT / VITT

Hematologist should be consulted whenever such suspicions arise

Early suspicion. Timely diagnosis. Right decision – Saves lives.”

Tushar Pandey: When Low Platelets Are Not ITP

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Health Hematology Hemostasis Hemostasis News Hemostasis Today heparin-induced thrombocytopenia HIT Immune thrombocytopenia ITP Medicine Thrombotic thrombocytopenic purpura TTP Tushar Pandey Vaccine Induced Thrombotic Thrombocytopenia VITT
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