Heghine Khachatryan: When Bleeding Speaks – Think Beyond Gynecology
Heghine Khachatryan, Editor-in-Chief of Hemostasis Today, Head of Hemophilia and Thrombosis Center at Yeolyan Hematology and Oncology Center, shared a post on LinkedIn:
“When Bleeding Speaks – Think Beyond Gynecology
Heavy menstrual bleeding is not just a symptom – it is a diagnostic signal.
Up to 24% of women with HMB may have von Willebrand disease, the most common inherited bleeding disorder – yet often missed.
Red Flags
- Menorrhagia from menarche
- Bleeding more than 7 days
- Iron deficiency anemia
- Postpartum/surgical bleeding
Family history
- Not symptoms – diagnostic alarms
- Think VWD When
- Bleeding is disproportionate
- Treatment response is poor
- Multisite bleeding exists
- Pregnancy is complicated
Approach
Don’t treat in silos
- Hematology plus Gynecology
- vWF testing (activity, antigen, FVIII)
- Risk assessment before surgery/pregnancy
Treatment is equal to Mechanism minus Based
- Hormonal therapy
- Tranexamic acid
- DDAVP / vWF concentrates
Core Message
- Treating bleeding alone is equal to incomplete care
- Identifying cause is equal to changing outcomes
Final Thought
Every unexplained bleeding in a woman deserves a hemostasis workup.
Because sometimes,
‘just a period’ is a missed diagnosis.”
Salih Ehsan, Chief Executive Officer at Kulsoom Society of hematology, shared Heghine Khachatryan’s post on LinkedIn, adding:
“During HMB, a history of multi site bleeding (gum bleeding, Epistaxis , injection site bruising, purpuric skin rashes) , history of recurrent mucocutaneous bleeding since childhood.
Family history of disproportionate bleeding ( in male and female also) are very helpful to suspect vWD.
Most common and under diagnosed bleeding disorder in Gynecology.
Even if a male child with hemophilia, always take a gynecology history from his mother also.”

Other posts featuring Heghine Khachatryan and Salih Ehsan on Hemostasis Today.
-
Apr 29, 2026, 15:48Kriti Batni: Happy to Share on Our Chapter Being Published in Medicine Update 2026
-
Apr 29, 2026, 15:46Dima Shulkin: Comparing HALP and PIV for Mortality Prediction in ACS
-
Apr 29, 2026, 15:44Sonal Sonu: Securing First Prize in Research Oral Presentation at the CME
-
Apr 29, 2026, 15:43Andrew Shaw: Long COVID First Diagnostic Classification with 69% accuracy
-
Apr 29, 2026, 15:41Yazan Abou-Ismail: Contributing Evidence-Based Topic Review on the Evaluation of Easy Bruising
-
Apr 29, 2026, 15:36Mohamed Sherif Salem: Expanding the Role of Tenecteplase in Acute Ischemic Stroke
-
Apr 29, 2026, 15:31WFH Humanitarian Aid Program Reflects on a Result of Years of Consistent Work with AHTA – Yeolyan Hematology and Oncology Center
-
Apr 29, 2026, 15:29Behnood Bikdeli: A Landmark JACC Journals Issue on Pulmonary Embolism
-
Apr 29, 2026, 15:01Patrick James Lynch: Speaking About the Risks and Benefits of Rebalancing Agents to Treat Hemophilia