International Journal of Stroke/X
May 7, 2026, 15:14
Meta-analysis of RCTs – International Journal of Stroke
International Journal of Stroke shared a post on X about a recent article by Fuxia Yang, adding:
”Meta-analysis of RCTs
In patients without clear anticoagulation indication, coagulation‑pathway therapies did not reduce covert brain infarcts (CBI) vs antiplatelets.
Composite endpoints dominated by CBI may not reflect clinical stroke benefit.”
Title: Antithrombotic Strategies Targeting the Coagulation Pathway and Incident Covert Brain Infarction: A Systematic Review and Meta-analysis of Randomized Trials
Authors: Fuxia Yang, Lu Wang, Xiao Wu, Lulan Li, Xueqiao Jiao, Fangfang Zhang, Xunming Ji, and Xiuhai Guo
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