Irina Portier: How Heme-Driven Platelet Signaling Worsens Malaria Neuropathogenesis
Irina Portier, Postdoctoral Researcher at Washington University in St. Louis, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Blood, adding:
“How does platelet mTOR contribute to cerebral malaria, and how does heme trigger these events?
I’m excited to share that our latest paper addressing these questions is now published in Blood.
Huge thanks to my mentors and collaborators Robert Campbell, Matthew Rondina, Frederik Denorme, Izabella Andrianova, Paul Sigala, Tracey Lamb, Neal Tolley, Yasuhiro Kosaka, Guy Zimmerman, Hugo Castro-Faria-Neto and Craig Morrell for their support and contributions.
We are especially honored to have our work featured on the cover and highlighted in the Blood podcast.
Also check out the insightful commentary accompanying our article.”
Title: Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR
Authors: Irina Portier, Frederik Denorme, Neal D. Tolley, Yasuhiro Kosaka, Izabella Andrianova, Paul A. Sigala, Tracey J. Lamb, Guy A. Zimmerman, Hugo C. Castro-Faria-Neto, Craig N. Morrell, Matthew T. Rondina, Robert A. Campbell

Stay updated on all scientific advances with Hemostasis Today.
-
Oct 8, 2026, 17:00Sally Mandour: Platelet Size And Shape Can Reveal The Diagnosis
-
Oct 8, 2026, 16:49Neil Morgan: Advancing Understanding Of Bleeding Disorders Of Unknown Cause
-
Oct 8, 2026, 16:38Beverley Hunt: Advancing Pulmonary Embolism Care Through Collaboration And Learning
-
Oct 8, 2026, 16:19Cedric Hermans: Six Webinars Advancing Haemophilia Care And Beyond
-
Oct 8, 2026, 16:09Luana Banu: Every Donation Connects A Human Chain
-
Oct 8, 2026, 15:51Khaled Musallam: A New Era In Thalassemia Care
-
Oct 8, 2026, 15:40Juan J. Ortiz։ Catheter Directed Therapy In Pulmonary Embolism
-
Oct 8, 2026, 15:34Petros Kountouris: Geostatistical Modelling Maps Global β-Thalassaemia Carrier Prevalence
-
Oct 8, 2026, 15:14Renzo Mancuso: Human Stem Cell Model Reveals Progenitor Fate in Tissue Macrophages