Irina Portier: How Heme-Driven Platelet Signaling Worsens Malaria Neuropathogenesis
Irina Portier, Postdoctoral Researcher at Washington University in St. Louis, shared a post on LinkedIn about a recent article she and her colleagues co-authored, published in Blood, adding:
“How does platelet mTOR contribute to cerebral malaria, and how does heme trigger these events?
I’m excited to share that our latest paper addressing these questions is now published in Blood.
Huge thanks to my mentors and collaborators Robert Campbell, Matthew Rondina, Frederik Denorme, Izabella Andrianova, Paul Sigala, Tracey Lamb, Neal Tolley, Yasuhiro Kosaka, Guy Zimmerman, Hugo Castro-Faria-Neto and Craig Morrell for their support and contributions.
We are especially honored to have our work featured on the cover and highlighted in the Blood podcast.
Also check out the insightful commentary accompanying our article.”
Title: Heme-induced ITAM signaling exacerbates malaria-associated neuropathogenesis through activation of platelet mTOR
Authors: Irina Portier, Frederik Denorme, Neal D. Tolley, Yasuhiro Kosaka, Izabella Andrianova, Paul A. Sigala, Tracey J. Lamb, Guy A. Zimmerman, Hugo C. Castro-Faria-Neto, Craig N. Morrell, Matthew T. Rondina, Robert A. Campbell
Stay updated on all scientific advances with Hemostasis Today.
-
May 16, 2026, 14:23Tom Ferry: ECMO Weaning Begins at the Circuit, Not the Bedside
-
May 16, 2026, 14:05Amir Sedighi: The Hidden Risk in Global Plasma Supply Strategy
-
May 16, 2026, 14:03Ali Saad Al-shammari: Exploring the Role of SGLT2 Inhibitors After TAVI
-
May 16, 2026, 13:49Priscilla Chassama: Expanding Healthcare Access for Children Living with Sickle Cell Disease in Geita
-
May 16, 2026, 12:00Anna Oleksiak: Is Thrombocytopenia in Critical Cardiac Care HIT?
-
May 16, 2026, 11:29Kim Gannon: Women Have Unique Stroke Risk Factors and The Warning Signs Can Look Different
-
May 16, 2026, 11:18Maciej Banach: What Is The Optimal Sleep Duration to Reduce Stroke Risk?
-
May 16, 2026, 11:17Understanding Cardiovascular Thrombosis and Myocarditis – UT Southwestern Heart and Vascular
-
May 16, 2026, 11:01Lijing L. Yan: The Implementation Gap – How South Korea Cut Stroke Deaths by 87%