Alejandro Gonzalez Veliz: What If Inflammation Is the Hidden Driver of Cardiovascular Disease?
Alejandro González Veliz, Interventional Cardiologist at Institute of Cardiology and Cardiovascular Surgery, shared a post on LinkedIn:
“What if inflammation is the hidden driver of cardiovascular disease?
For decades, cholesterol has been the main focus of prevention. But growing evidence shows that chronic low-grade inflammation plays a central role in atherosclerosis, plaque rupture, myocardial infarction, and heart failure.
Inflammation promotes endothelial dysfunction, foam cell formation, and vulnerable plaques.
High-sensitivity C-reactive protein (hsCRP) helps identify residual inflammatory risk—even when LDL cholesterol is well controlled.
Clinical trials such as CANTOS, COLCOT, and LoDoCo2 demonstrated that targeting inflammation can reduce cardiovascular events.
The good news?
Lifestyle remains one of the most powerful anti-inflammatory therapies:
- Mediterranean diet
- Regular exercise
- Smoking cessation
- Healthy weight management
The future of cardiovascular prevention is no longer just about lowering cholesterol. It’s about extinguishing the silent fire within the arteries.”

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