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November, 2026
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Wenxue Ma: An Integrative Framework for Macrophage-Mediated Therapeutic Resistance in Cancer
Nov 8, 2026, 19:26

Wenxue Ma: An Integrative Framework for Macrophage-Mediated Therapeutic Resistance in Cancer

Wenxue Ma, Editorial Board Member at Annals of Translational Medicine, External Expert Reviewer at Raine Medical Research Foundation, European Research Council (ERC) and NCN National Science Centre, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Drug Resistance Updates, adding:

“I would like to share a newly accepted review ‘Macrophage-centered resistance programs in cancer: A unified framework for therapeutic resistance and precision immunotherapy,’ published in Drug Resistance Updates.

We propose an integrative framework encompassing four interconnected macrophage-centered resistance programs: lipid-associated, matrix-remodeling, glyco-immune, and metabolic that contribute to immune evasion and therapeutic resistance.

This framework highlights potential strategies for overcoming treatment resistance through macrophage-directed interventions and biomarker-guided precision immunotherapy.”

Title: Macrophage-centered resistance programs in cancer: A unified framework for therapeutic resistance and precision immunotherapy

Authors: Yanjun Li, Suling Xu, Huangze Xie, Qingqing Wang, Lingeng Lu, Wenxue Ma

Wenxue Ma

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