Saleh Shamse Basha/LinkedIn
Jun 26, 2026, 07:10
Saleh Shamse Basha: Why APTT Alone Can Be Misleading During UFH Monitoring
Saleh Shamse Basha, Senior Hematology Technologist (Reference Lab, HQ) at PureLab, shared a post on LinkedIn:
“A patient post surgical inflammation on unfractionated heparin (UFH).
APTT: 66 sec.
In thise case can you relay on APTT alone to monitor the UFH??
The answer is : No.
But, Why?
During the acute-phase response, Factor VIII is often elevated.
Increased FVIII shortens the APTT, meaning that an APTT of 66 seconds may underestimate the true anticoagulant effect of UFH.
That’s the trap.
That’s why we should use Anti-Xa assay while monitoring patient on UFH.”
Stay updated with Hemostasis Today.
-
Aug 11, 2026, 05:53Isaac Okello: Strengthening Sickle Cell Advocacy in Uganda
-
Aug 11, 2026, 05:38Rami Unterman: A Simple New Biomarker for Fibrotic ILDs
-
Aug 11, 2026, 04:10Haroun Gajraj: CLaCS vs Sclerotherapy – What Does the Evidence Show
-
Aug 11, 2026, 02:54Tareq Abadl: The Ultimate Guide to Clinically Significant Antibodies
-
Aug 10, 2026, 17:35Chokri Ben Lamine: Balancing Holistic Care and Precision in Hematology
-
Aug 10, 2026, 17:14Anna Stanizzi: Patient Blood Management as a New Model of Personalized Care
-
Aug 10, 2026, 17:12Odong Christopher: New Research on Ischemic Stroke Prediction in Uganda
-
Aug 10, 2026, 16:58Jeff Szer AM: Advancing the Management of Paroxysmal Nocturnal Hemoglobinuria
-
Aug 10, 2026, 16:51Suebsarn Ruksakulpiwat։ A New Milestone in the Development of the Stroke Risk Screening Scales