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Tareq Abadl: Post-Transfusion Reactions – Can You Identify the Cause?
Tareq Abadl/LinkedIn
Jul 5, 2026, 19:53

Tareq Abadl: Post-Transfusion Reactions – Can You Identify the Cause?

Tareq Abadl, Medical Lab Specialist, shared a post on LinkedIn:

“Post-Transfusion Reactions: Can You Identify the Cause?

Not all post-transfusion reactions are the same.

As a Medical Laboratory Scientist, recognizing the type of reaction is essential because the laboratory plays a critical role in the investigation.

Common Post-Transfusion Reactions:

Acute Hemolytic Transfusion Reaction (AHTR)

Usually caused by ABO incompatibility.

Symptoms: Fever, chills, back pain, hypotension, hemoglobinuria.

Medical emergency requiring immediate investigation.

Febrile Non-Hemolytic Transfusion Reaction (FNHTR)

Caused by cytokines or recipient antibodies reacting with donor leukocytes.

Symptoms: Fever (≥1°C increase) and chills without evidence of hemolysis.

One of the most common transfusion reactions.

Allergic Transfusion Reaction

Caused by hypersensitivity to donor plasma proteins.

Symptoms: Itching, urticaria, and skin rash.

Usually mild but should always be assessed.

Blood Bank Investigation May Include:

  • Stop the transfusion immediately.
  • Perform a clerical check.
  • Repeat ABO/Rh testing.
  • Direct Antiglobulin Test (DAT).
  • Inspect plasma for hemolysis.
  • Additional testing as clinically indicated.

Remember: Every suspected transfusion reaction must be investigated—even when compatibility testing is acceptable.

Early recognition and prompt laboratory investigation are essential for patient safety.”

Tareq Abadl

Other posts featuring Tareq Abadl on Hemostasis Today.

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