Mark Lewis/netrf.org
Aug 18, 2025, 09:45
Mark Lewis: aPTT Pathway—What Activates What
Mark Lewis, Director of Gastrointestinal Oncology at Intermountain Healthcare in Utah, shared a post X:
“So factor XII is activated when it’s exposed to collagen, kallikrein, and high molecular weight kininogen, which in turn activates factor XI into XIa. With a calcium ion, factor XIa activates factor IX. Then, FIXa, FVIIIa, and calcium activate factor X…”
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