Hemostasis Today
NewsFeed
Headlines Hematology Health Medicine VTE ASH Plasma Donation
September, 2026
September 2026
M T W T F S S
 123456
78910111213
14151617181920
21222324252627
282930  
Jehad Khamaysa: Budd-Chiari Syndrome as the Initial Presentation of Behçet’s Disease in a 16-Year-Old
Jehad Khamaysa/LinkedIn
Sep 11, 2026, 16:47

Jehad Khamaysa: Budd-Chiari Syndrome as the Initial Presentation of Behçet’s Disease in a 16-Year-Old

Jehad Khamaysa, Head of Radiology Department at Turkish Governmental Hospital, shared a post on LinkedIn:

“Did you know Behçet’s disease can first appear as a life-threatening liver condition, years before its classic signs show up?

We published a case of a 16-year-old girl who presented with fatigue and bone pain that progressed to abdominal distension and hepatosplenomegaly.

Imaging confirmed Budd-Chiari syndrome – hepatic vein obstruction – as the first manifestation of Behçet’s disease.

Genetic testing added a second layer of risk: a Factor V Leiden mutation alongside the HLA-B51 allele associated with BD.

  • Vascular involvement can be Behçet’s disease’s presenting feature, not a late complication – especially in adolescents with unexplained hepatosplenomegaly.
  • Inherited thrombophilia and BD’s own prothrombotic tendency compound each other, raising clot risk significantly.
  • Early imaging plus genetic workup drove management: aggressive anticoagulation led to partial recanalization and clinical stabilization.

Published in 2025, co-authored with colleagues from Palestine.

Have you seen atypical vascular presentations of Behçet’s disease in your practice?”

Stay updated with Hemostasis Today.

Behçet's disease Budd-Chiari Syndrome Health Hematology Hemostasis Hemostasis News Hemostasis Today Jehad Khamaysa Medicine
NewsFeed