Massimo Martino: VEN-DEC-GITMO – Advancing AML Treatment in Older Patients
Massimo Martino, President of GITMO, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Blood Advances, adding:
“Published in Blood Advances (official journal of the American Society of Hematology, ASH):
The Italian multicenter study VEN-DEC-GITMO — ‘A Curative-Intent Treatment Programme in Older AML: Mature Post-Transplant Results from the VEN-DEC-GITMO Study.’
The study involved over 30 Italian hematology centers (GITMO) and confirms that the venetoclax-decitabine combination can serve as an effective ‘bridge to transplant’ for older patients with acute myeloid leukemia, enabling them to reach allogeneic transplant in optimal clinical condition.
2-year results: overall survival of 52.8%, disease-free survival of 50.9%, and a relapse incidence contained at 20.1% — remarkable outcomes for a population with a median age of 68.5 years and high-risk disease.
Among the participating centers, an important contribution came from GOM ‘Bianchi-Melacrino-Morelli‘ in Reggio Calabria, with Massimo Martino and Caterina Alati, reflecting the active role of Calabrian hematology in national and international clinical research.
A further step forward in defining curative-intent treatment pathways for older AML patients.”
Title: A Curative-Intent Treatment Programme in Older AML: Mature Post-Transplant Results from the VEN-DEC-GITMO Study
Authors: Daniele Avenoso, Mirko Farina, Alessandro Leoni, Nicola Polverelli, Simona Bernardi, Stella Santarone, Erika Borlenghi, Francesco Onida, Luca Castagna, Stefania Bramanti, Angelo Michele Carella, Roberto Sorasio, Caterina Alati, Attilio Olivieri, Germana Beltrami, Carmen di Grazia, Antonio Curti, Francesca Bonifazi, Calogero Vetro, Salvatore Leotta, Valentina Mancini, Giovanni Grillo, Elisabetta Terruzzi, Massimo Bernardi, Alessandro Bruno, Piero Galieni, Pellegrino Musto, Raffaella Cerretti, Luisa Giaccone, Cristina Skert, Vera Radici, Marika Vezzoli, Stefano Calza, Luca Garuffo, Cristian Bonvicini, Simone Pellizzeri, Michele Malagola, Massimo Martino, Domenico Russo
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