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October, 2026
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Anjali Pandey: The Morphologic Clues to MDS With del(5q)
Oct 9, 2026, 10:32

Anjali Pandey: The Morphologic Clues to MDS With del(5q)

Anjali Pandey, Pathologist, Chief of Dr Lal PathLabs, shared a post on LinkedIn:

“Phenotypic Clues in Myeloid Neoplasms

Post 6: MDS with isolated delivery(5q)

The classic ‘hypolobated megakaryocytes ‘ story.

  • Monolobated or hypolobated negkaryocytes ( often 30-85% of megas)
  • Macrocytic Anemia
  • Minimal dysplasia in other lineages
  • No Auer rods

WHO stills requires Anemia and megakaryocytic dysplasia ICC is more lenient .

A morphologic clue that can guide rapid FISH for 5q.”

Anjali Pandey: The Morphologic Clues to MDS With del(5q)

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