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Maria Abbattista: From Combined Hormonal Contraceptives to Cerebral Vein Thrombosis
Maria Abbattista/LinkedIn
Sep 8, 2025, 06:19

Maria Abbattista: From Combined Hormonal Contraceptives to Cerebral Vein Thrombosis

Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn:

”The risk of cerebral vein thrombosis associated with different types of combined hormonal contraceptives: a case-control study

In this case-control study of 206 women with CVT and 868 controls, combined hormonal contraceptive (CHC) use was associated with a 10-fold higher risk of CVT.

Risk increased with higher estrogen doses and was particularly elevated with fourth-generation pills (OR 28.3).

Progestin-only and variable-dose CHCs carried a 6-fold increased risk.

Importantly, thrombophilia and positive family history had synergistic effects, with odds ratios exceeding 200 in some subgroups.”

Read the full paper in JTH.

Article: The risk of cerebral vein thrombosis associated with different types of combined hormonal contraceptives: a case-control study

Authors: Maria Abbattista, Addolorata Truma, Ida Martinelli, Francesca Gianniello, Serena M. Passamonti, Marco Capecchi, Andrea Artoni, Flora Peyvandi, Paolo Bucciarelli

Maria Abbattista: From Combined Hormonal Contraceptives to Cerebral Vein Thrombosis

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Addolorata Truma Andrea Artoni cerebral vein thrombosis CHC CVT Flora Peyvandi Francesca Gianniello Health Hematology Hemostasis Hemostasis Today Ida Martinelli JTH Marco Capecchi Maria Abbattista Medicine Paolo Bucciarelli Serena M. Passamonti thrombosis
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