Evi Loos: Can PRP Improve Pain in Thumb Base Osteoarthritis?
Evi Loos, PhD Candidate Plastic Surgery at UMC Utrecht, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in BMJ Open, adding:
“Happy to share that our study protocol of the Thumbs-Up trial has been published in BMJ Open.
Thumb base osteoarthritis is common and can severely limit hand function, while non-surgical treatments often offer only temporary relief. PRP is increasingly used, but evidence in the thumb base is limited, and the platelet dose that is actually injected is rarely reported.
In our double-blind trial, 88 patients receive a single ultrasound-guided injection of either high-concentration, leukocyte-poor PRP or saline. We measure the delivered platelet dose for every participant and follow patients for 12 months, with pain as the primary outcome.
We hope this trial gives a clearer answer to whether PRP has a place in the treatment of thumb base osteoarthritis. Recruitment is ongoing at GOED Medical Center in Breda, the Netherlands.
Thanks to my co-authors Mustafa Uguten, Remco Otten, Harrie Weinans, Henk Coert and Joris van Dongen.”
Title: Thumb base osteoarthritis: ultrasound-guided platelet-rich plasma versus placebo injection (thumbs-up study) – study protocol of a randomised double-blind placebo-controlled trial
Authors: Evi Maria Gerarda Loos, Mustafa Uguten, Remco Otten, Harrie H. Weinans, J. Henk Coert, Joris van Dongen
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