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Edwin Ofori Atta: High-Dose Vitamin C and Vascular Function

Edwin Ofori Atta/LinkedIn

Apr 7, 2026, 15:41

Edwin Ofori Atta: High-Dose Vitamin C and Vascular Function

Edwin Ofori Atta, Head Of Pharmacy at Kumasi Hospital, shared a post on LinkedIn:

“Taking 2 g of vitamin C reduces arterial stiffness by about 9.6 percent within 6 hours and reduces platelet aggregation by about 35%, which may help lower the risk of blood clots.

Specifically high-dose vitamin C reducing arterial stiffness and platelet aggregation within 6 hours, are supported by clinical studies on cardiovascular health.

Vitamin C functions as a powerful antioxidant, scavenging free radicals and improving the bioavailability of nitric oxide.

Increased nitric oxide bioavailability allows blood vessels to relax (vasodilation) and prevents platelets from sticking together.

Double-blind, randomized study found that acute oral administration of high-dose vitamin C significantly increased plasma levels, which reduced the augmentation index (a key measure of arterial stiffness) within 6 hours.

While this study was on healthy individuals, similar studies indicate that vitamin C provides significant cardiovascular benefits by protecting the endothelium (vessel lining) and reducing platelet activation, particularly in individuals with high oxidative stress.”

Edwin Ofori Atta: High-Dose Vitamin C and Vascular Function