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Francis Kynaston-Pearson: Why Randomised Controlled Trials Are the Gold Standard in Clinical Research
Mar 16, 2026, 15:44

Francis Kynaston-Pearson: Why Randomised Controlled Trials Are the Gold Standard in Clinical Research

Francis Kynaston-Pearson, Consultant Rheumatologist at Mediclinic Middle East, shared a post on LinkedIn:

The randomised control trial (RCT) – the ‘gold standard’ for clinical evidence.

If that is so, why is all evidence not gathered in such a manner.

For those in research, the answer is evident but doctors and scientists forget that the complexities of the nuts and bolts of a quality trial are not common knowledge of our patients.

Not all questions can be answered with an RCT, not to mention the cost in setting one up.

Trials with mild or moderate methodological failing or negative results may not even get published, with the hard work never known outside the investigating team.

For anyone who wanted a quick overview of RCTs but was a little afraid or embarrassed to ask, here is a quick video for you.”

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